Researchers b "New York Abu Dhabi" They invent a technology that paves the way for a transformation in cancer treatment
Abu Dhabi, December 4 / WAM / Researchers at New York University Abu Dhabi have succeeded in developing a simple, low-cost tool called “Spheromatrix”, with the aim of growing, freezing and storing tumor models to test treatments against cancer.
The tool relies on “filter paper” specifically designed to support the growth of tumor masses in a controlled and reproducible manner. Unlike traditional methods that are usually expensive, complex, and cannot be stored for a long time, this tool provides researchers with a way to store a huge collection of tumor models ready for use, so they can be heated and tested when needed.
The team that conducted the study was led by Dr. Mohammed Qasaima, Associate Professor of Mechanical and Bioengineering, along with first author and co-researcher Dr. Ayoub Kulli and his colleagues in the Advanced Microfluidics and Miniaturized Devices Laboratory at NYU Abu Dhabi (AMMLab).
Dr. Muhammad Qasaimeh explained that this technology represents an important step in cancer research, noting that the tool has a structure based on fibers that form a biocompatible environment with cells, which allows tumor models to develop like real cancerous tumors. Storing these models for long-term use may contribute to accelerating the pre-clinical testing phase, reduces reliance on animal models, and opens new horizons for patient-oriented research.
The team tested the effect of available chemotherapy drugs on brain tumor models implanted in the innovative tool, which responded similarly to the response of tumors in patients’ bodies, indicating the possibility of developing reproducible, realistic and scalable drug testing systems based on the new technology.
Spherometrics technology can reduce costs and duration of pre-clinical testing, provides humane alternatives to animal testing, and paves the way for patient-oriented precision oncology applications.
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